The Sistine Madonna is an oil painting by Raphael completed between 1513 and 1514 and stored in the Old Masters Picture Gallery in Dresden. For more than two centuries, the work in its original location has remained almost unknown, but in 1754 Augustus III, Prince of Saxony, purchased the painting, generating wide interest in it also due to the large amount he paid for it. During the 1800s proponents of classicism and romanticism discovered the painting and helped to make it one of the most admired, cited and studied works of figurative art. Today the "Sistine Madonna" is considered one of the icons of the Renaissance and renowned worldwide in the same way as Leonardo da Vinci's "Mona Lisa" and Botticelli's "Venice". An interpretation of this work by artist Daniela Fusco has been chosen by the Philatelic and Numismatic Office to mark the celebration of the 500th anniversary of the creation of the masterpiece. On the reverse of the 100 euro coin, the first numismatic gold issue under the Pontificate of Pope Francis, two details of the painting are depicted: the Virgin holding the Christ child in her arms and the two small angels at her feet.